Toward Understanding the Catalytic Mechanism of Human Paraoxonase 1: Site-Specific Mutagenesis at Position 192

Human paraoxonase 1 (h-PON1) is a serum enzyme that can hydrolyze a variety of substrates. The enzyme exhibits anti-inflammatory, anti-oxidative, anti-atherogenic, anti-diabetic, anti-microbial and organophosphate-hydrolyzing activities. Thus, h-PON1 is a strong candidate for the development of ther...

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Detalles Bibliográficos
Autores principales: Aggarwal, Geetika, Prajapati, Rameshwar, Tripathy, Rajan K., Bajaj, Priyanka, Iyengar, A. R. Satvik, Sangamwar, Abhay T., Pande, Abhay H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734699/
https://www.ncbi.nlm.nih.gov/pubmed/26829396
http://dx.doi.org/10.1371/journal.pone.0147999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734699/
https://www.ncbi.nlm.nih.gov/pubmed/26829396
http://dx.doi.org/10.1371/journal.pone.0147999

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