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Emerging treatments in Castleman disease – a critical appraisal of siltuximab
Castleman disease (CD) is a rare, heterogeneous lymphoproliferative disorder for which no standard of care currently exists. Evidence that the pathophysiology of CD is fueled by excessive interleukin-6 (IL-6) has led to considerable interest in therapeutic targeting of this cytokine. Siltuximab, a c...
| Autores principales: | , |
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| Formato: | Online Artigo Texto |
| Idioma: | English |
| Publicado: |
Dove Medical Press
2016
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| Acceso en liña: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734738/ https://www.ncbi.nlm.nih.gov/pubmed/26869762 http://dx.doi.org/10.2147/BTT.S60523 |