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Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross

The extent and strength of epistasis is commonly unresolved in genetic studies, and observed epistasis is often difficult to interpret in terms of biological consequences or overall genetic architecture. We investigated the prevalence and consequences of epistasis by analyzing four body composition...

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Detalles Bibliográficos
Autores principales: Tyler, Anna L., Donahue, Leah Rae, Churchill, Gary A., Carter, Gregory W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734753/
https://www.ncbi.nlm.nih.gov/pubmed/26828925
http://dx.doi.org/10.1371/journal.pgen.1005805

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