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Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross
The extent and strength of epistasis is commonly unresolved in genetic studies, and observed epistasis is often difficult to interpret in terms of biological consequences or overall genetic architecture. We investigated the prevalence and consequences of epistasis by analyzing four body composition...
Autores principales: | Tyler, Anna L., Donahue, Leah Rae, Churchill, Gary A., Carter, Gregory W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734753/ https://www.ncbi.nlm.nih.gov/pubmed/26828925 http://dx.doi.org/10.1371/journal.pgen.1005805 |
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