A novel type of self-assembled nanoparticles as targeted gene carriers: an application for plasmid DNA and antimicroRNA oligonucleotide delivery

In this study, a new type of amphiphilic cetylated polyethyleneimine (PEI) was synthesized, and then polylactic-co-glycolic acid (PLGA)/cetylated PEI/hyaluronic acid nanoparticles (PCPH NPs) were developed by self-assembly as a novel type of gene-delivering vehicle. The PCPH NPs showed good DNA-cond...

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Detalles Bibliográficos
Autores principales: Zhu, Yanliang, Liang, Gaofeng, Sun, Bo, Tian, Tian, Hu, Feihu, Xiao, Zhongdang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734819/
https://www.ncbi.nlm.nih.gov/pubmed/26869785
http://dx.doi.org/10.2147/IJN.S84927

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