IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment

Colorectal cancer (CRC) metastatic dissemination to the liver is one of the most life‐threatening malignancies in humans and represents the leading cause of CRC‐related mortality. Herein, we adopted a gene transfer strategy into mouse hematopoietic stem/progenitor cells to generate immune‐competent...

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Detalles Bibliográficos
Autores principales: Catarinella, Mario, Monestiroli, Andrea, Escobar, Giulia, Fiocchi, Amleto, Tran, Ngoc Lan, Aiolfi, Roberto, Marra, Paolo, Esposito, Antonio, Cipriani, Federica, Aldrighetti, Luca, Iannacone, Matteo, Naldini, Luigi, Guidotti, Luca G, Sitia, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734840/
https://www.ncbi.nlm.nih.gov/pubmed/26769348
http://dx.doi.org/10.15252/emmm.201505395

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