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Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1
Reactivation of HIV gene expression in latently infected cells together with an efficient cART has been proposed as an adjuvant therapy aimed at eliminating/decreasing the reservoir size. Results from HIV clinical trials using deacetylase inhibitors (HDACIs) question the efficiency of these latency‐...
Autores principales: | Bouchat, Sophie, Delacourt, Nadège, Kula, Anna, Darcis, Gilles, Van Driessche, Benoit, Corazza, Francis, Gatot, Jean‐Stéphane, Melard, Adeline, Vanhulle, Caroline, Kabeya, Kabamba, Pardons, Marion, Avettand‐Fenoel, Véronique, Clumeck, Nathan, De Wit, Stéphane, Rohr, Olivier, Rouzioux, Christine, Van Lint, Carine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734845/ https://www.ncbi.nlm.nih.gov/pubmed/26681773 http://dx.doi.org/10.15252/emmm.201505557 |
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