Cargando…

Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study

PURPOSE: Telomere attrition and corresponding cellular senescence of the retinal pigment epithelium contribute to the changes of age-related macular degeneration. Activation of the enzyme telomerase can add telomeric DNA to retinal pigment epithelium chromosomal ends and has been proposed as a treat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dow, Coad Thomas, Harley, Calvin B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Clinical Trial Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734847/ https://www.ncbi.nlm.nih.gov/pubmed/26869760 http://dx.doi.org/10.2147/OPTH.S100042

Ejemplares similares

Impact of Prophylactic Ranibizumab to Prevent Neovascular Age-Related Macular Degeneration on Eyes With Intermediate Age-Related Macular Degeneration
por: Chan, Clement K., et al.
Publicado: (2023)

Functional Outcomes of the Low Vision Depression Prevention Trial in Age-Related Macular Degeneration
por: Deemer, Ashley D., et al.
Publicado: (2017)

Are Dilated Fundus Examinations Needed for OCT-Guided Retreatment of Exudative Age-Related Macular Degeneration? A Prospective, Randomized, Pilot Study
por: Solomon, Sharon D, et al.
Publicado: (2021)

Update on Clinical Trials in Dry Age-related Macular Degeneration
por: Taskintuna, Ibrahim, et al.
Publicado: (2016)

Combination of ranibizumab and indomethacin for neovascular age-related macular degeneration: randomized controlled trial
por: Russo, Andrea, et al.
Publicado: (2018)

Safety and Tolerability of Intravitreal Carotuximab (DE-122) in Patients With Persistent Exudative Age-Related Macular Degeneration: A Phase I Study
por: Gonzalez, Victor H., et al.
Publicado: (2021)

Impact of Modifying Abicipar Manufacturing Process in Patients with Neovascular Age-Related Macular Degeneration: MAPLE Study Results
por: Callanan, David, et al.
Publicado: (2023)

Management of Neovascular Age-related Macular Degeneration: A Review on Landmark Randomized Controlled Trials
por: Agarwal, Aniruddha, et al.
Publicado: (2016)

Intravitreal use of bone marrow mononuclear fraction containing CD34(+) stem cells in patients with atrophic age-related macular degeneration
por: Cotrim, Carina Costa, et al.
Publicado: (2017)

One-year outcome of intravitreal aflibercept injection for age-related macular degeneration resistant to ranibizumab: rapid morphologic recovery and subsequent visual improvement
por: Hirakata, Toshiaki, et al.
Publicado: (2016)

Relationship between macular pigment and visual function in subjects with early age-related macular degeneration
por: Akuffo, Kwadwo Owusu, et al.
Publicado: (2017)

Age-related macular degeneration: choroidal ischaemia?
por: Coleman, D Jackson, et al.
Publicado: (2013)

Prevalence of age-related macular degeneration in the Republic of Ireland
por: Akuffo, Kwadwo Owusu, et al.
Publicado: (2015)

Effect of Supplemental Lutein and Zeaxanthin on Serum, Macular Pigmentation, and Visual Performance in Patients with Early Age-Related Macular Degeneration
por: Huang, Yang-Mu, et al.
Publicado: (2015)

Genetic testing in women with early-onset breast cancer: a Traceback pilot study
por: Augustinsson, Annelie, et al.
Publicado: (2021)

Sustained supplementation and monitored response with differing carotenoid formulations in early age-related macular degeneration
por: Akuffo, K O, et al.
Publicado: (2015)

Association of Visual Function Measures with Drusen Volume in Early Stages of Age-Related Macular Degeneration
por: Pondorfer, Susanne G., et al.
Publicado: (2020)

Phacoemulsification Surgery in Eyes with Neovascular Age-Related Macular Degeneration
por: Grixti, Andre, et al.
Publicado: (2014)

Macular and Plasma Xanthophylls Are Higher in Age-related Macular Degeneration than in Normal Aging: Alabama Study on Early Age-related Macular Degeneration 2 Baseline
por: McGwin, Gerald, et al.
Publicado: (2022)

Combination of Aflibercept and Bromfenac Therapy in Age-Related Macular Degeneration: A Pilot Study Aflibercept and Bromfenac in AMD
por: Wyględowska-Promieńska, Dorota, et al.
Publicado: (2015)

Dietary Intervention With a Targeted Micronutrient Formulation Reduces the Visual Discomfort Associated With Vitreous Degeneration
por: Ankamah, Emmanuel, et al.
Publicado: (2021)

Effect of Phacoemulsification on Visual Acuity and Macular Morphology in Patients with Wet Age-Related Macular Degeneration
por: Figurska, Małgorzata, et al.
Publicado: (2018)

Telomerase and Cell Immortality: Applications in Research and Medicine
por: Harley, Calvin B.
Publicado: (2001)

Telomerase reactivation reverses tissue degeneration in aged telomerase deficient mice
por: Jaskelioff, Mariela, et al.
Publicado: (2010)

Early Responses to Intravitreal Ranibizumab in Typical Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy
por: Matsumiya, Wataru, et al.
Publicado: (2011)

Early Detection and Prevention of Age-Related Macular Degeneration
por: Seluarize, Gayathri, et al.
Publicado: (2023)

The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
por: Yildirim, Zuhal, et al.
Publicado: (2011)

Wide-Field Fluorescein Angiography in Wet Age-Related Macular Degeneration
por: Madhusudhan, Savitha, et al.
Publicado: (2014)

Genetic risk factors for late age-related macular degeneration in India
por: Rajendran, Anand, et al.
Publicado: (2018)

Fractal analysis of polypoidal choroidal neovascularisation in age-related macular degeneration
por: Serra, Rita, et al.
Publicado: (2021)

Intravitreal Dexamethasone in Patients with Wet Age-Related Macular Degeneration Resistant to Anti-VEGF: A Prospective Pilot Study
por: Giancipoli, Ermete, et al.
Publicado: (2018)

Relative Telomere Length Is Associated With Age-Related Macular Degeneration in Women
por: Koller, Adriana, et al.
Publicado: (2022)

Feasibility and benefits of group-based exercise in residential aged care adults: a pilot study for the GrACE programme
por: Fien, Samantha, et al.
Publicado: (2016)

Visualization of Dietary Patterns and Their Associations With Age-Related Macular Degeneration
por: Chiu, Chung-Jung, et al.
Publicado: (2017)

Pegaptanib sodium as maintenance therapy in neovascular age-related macular degeneration: the LEVEL study
por: Friberg, Thomas R, et al.
Publicado: (2010)

Age-related macular degeneration.
por: McConnell, V., et al.
Publicado: (2005)

Age-related macular degeneration
por: Querques, Giuseppe, et al.
Publicado: (2011)

Age-related macular degeneration
por: Mathenge, Wanjiku
Publicado: (2014)

Phase 1 Dose-Escalation Study of Plasma Kallikrein Inhibitor THR-149 for the Treatment of Diabetic Macular Edema
por: Dugel, Pravin U., et al.
Publicado: (2021)

Age-related macular degeneration and the aging eye
por: Ehrlich, Rita, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_n453l1udvni1v38ccdnqmgojvt