Ménétrier’s Disease: Its Mimickers and Pathogenesis

Ménétrier’s disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy. The pathogenesis of Ménétrier’s disease is not fully understood; however, it appears that the epidermal growth factor receptor (EGFR) ligand...

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Detalles Bibliográficos
Autores principales: Huh, Won Jae, Coffey, Robert J., Washington, Mary Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and the Korean Society for Cytopathology 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734964/
https://www.ncbi.nlm.nih.gov/pubmed/26689786
http://dx.doi.org/10.4132/jptm.2015.09.15
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author Huh, Won Jae
Coffey, Robert J.
Washington, Mary Kay
author_facet Huh, Won Jae
Coffey, Robert J.
Washington, Mary Kay
author_sort Huh, Won Jae
collection PubMed
description Ménétrier’s disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy. The pathogenesis of Ménétrier’s disease is not fully understood; however, it appears that the epidermal growth factor receptor (EGFR) ligand, transforming growth factor alpha, contributes to the pathogenesis of this disorder. In this review, we will discuss disease entities that can mimic Ménétrier’s disease and the role of EGFR signaling in Ménétrier’s disease.
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spelling pubmed-47349642016-02-09 Ménétrier’s Disease: Its Mimickers and Pathogenesis Huh, Won Jae Coffey, Robert J. Washington, Mary Kay J Pathol Transl Med Review Ménétrier’s disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy. The pathogenesis of Ménétrier’s disease is not fully understood; however, it appears that the epidermal growth factor receptor (EGFR) ligand, transforming growth factor alpha, contributes to the pathogenesis of this disorder. In this review, we will discuss disease entities that can mimic Ménétrier’s disease and the role of EGFR signaling in Ménétrier’s disease. The Korean Society of Pathologists and the Korean Society for Cytopathology 2016-01 2015-12-18 /pmc/articles/PMC4734964/ /pubmed/26689786 http://dx.doi.org/10.4132/jptm.2015.09.15 Text en © 2016 The Korean Society of Pathologists/The Korean Society for Cytopathology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Huh, Won Jae
Coffey, Robert J.
Washington, Mary Kay
Ménétrier’s Disease: Its Mimickers and Pathogenesis
title Ménétrier’s Disease: Its Mimickers and Pathogenesis
title_full Ménétrier’s Disease: Its Mimickers and Pathogenesis
title_fullStr Ménétrier’s Disease: Its Mimickers and Pathogenesis
title_full_unstemmed Ménétrier’s Disease: Its Mimickers and Pathogenesis
title_short Ménétrier’s Disease: Its Mimickers and Pathogenesis
title_sort ménétrier’s disease: its mimickers and pathogenesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734964/
https://www.ncbi.nlm.nih.gov/pubmed/26689786
http://dx.doi.org/10.4132/jptm.2015.09.15
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