Cargando…
Mechanism of Anti-α-Synuclein Immunotherapy
Immunization therapy targeting α-synuclein has emerged as a promising approach for Parkinson’s disease and perhaps for other synucleinopathies. Several antibodies have shown therapeutic effects in mouse models of synucleinopathies and have alleviated the pathological and behavioral phenotypes of the...
Autores principales: | Lee, Jun Sung, Lee, Seung-Jae |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Movement Disorders Society
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734990/ https://www.ncbi.nlm.nih.gov/pubmed/26828212 http://dx.doi.org/10.14802/jmd.15059 |
Ejemplares similares
-
α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
por: Tran, Hien T., et al.
Publicado: (2014) -
Modeling α-Synuclein Propagation with Preformed Fibril Injections
por: Chung, Hyun Kyung, et al.
Publicado: (2019) -
α-Synuclein and Mechanisms of Epigenetic Regulation
por: Surguchov, Andrei
Publicado: (2023) -
Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy
por: Spencer, Brian, et al.
Publicado: (2017) -
Statins suppress cell-to-cell propagation of α-synuclein by lowering cholesterol
por: Min, Joo-Ok, et al.
Publicado: (2023)