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Codimension-one bifurcation and stability analysis in an immunosuppressive infection model
One of the important medical problems is infectious diseases such as HIV and hepatitis which annually causes the death of many people. So it is important to study infectious diseases parametric models. In this paper, we investigate differential equations system of HIV and hepatitis (with delay and w...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735110/ https://www.ncbi.nlm.nih.gov/pubmed/26877904 http://dx.doi.org/10.1186/s40064-016-1737-0 |
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author | Dadi, Zohreh Alizade, Samira |
author_facet | Dadi, Zohreh Alizade, Samira |
author_sort | Dadi, Zohreh |
collection | PubMed |
description | One of the important medical problems is infectious diseases such as HIV and hepatitis which annually causes the death of many people. So it is important to study infectious diseases parametric models. In this paper, we investigate differential equations system of HIV and hepatitis (with delay and without delay) from the stability and codimension-one bifurcation point of view. We show that their dynamical behaviour will change when the parameters vary. We prove that this model has a saddle-node bifurcation and transcritical bifurcation when the delay parameter is absent. Also by using the center manifold theory, we show that the delay model has a saddle-node bifurcation. |
format | Online Article Text |
id | pubmed-4735110 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-47351102016-02-12 Codimension-one bifurcation and stability analysis in an immunosuppressive infection model Dadi, Zohreh Alizade, Samira Springerplus Research One of the important medical problems is infectious diseases such as HIV and hepatitis which annually causes the death of many people. So it is important to study infectious diseases parametric models. In this paper, we investigate differential equations system of HIV and hepatitis (with delay and without delay) from the stability and codimension-one bifurcation point of view. We show that their dynamical behaviour will change when the parameters vary. We prove that this model has a saddle-node bifurcation and transcritical bifurcation when the delay parameter is absent. Also by using the center manifold theory, we show that the delay model has a saddle-node bifurcation. Springer International Publishing 2016-02-01 /pmc/articles/PMC4735110/ /pubmed/26877904 http://dx.doi.org/10.1186/s40064-016-1737-0 Text en © Dadi and Alizade. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Research Dadi, Zohreh Alizade, Samira Codimension-one bifurcation and stability analysis in an immunosuppressive infection model |
title | Codimension-one bifurcation and stability analysis in an immunosuppressive infection model |
title_full | Codimension-one bifurcation and stability analysis in an immunosuppressive infection model |
title_fullStr | Codimension-one bifurcation and stability analysis in an immunosuppressive infection model |
title_full_unstemmed | Codimension-one bifurcation and stability analysis in an immunosuppressive infection model |
title_short | Codimension-one bifurcation and stability analysis in an immunosuppressive infection model |
title_sort | codimension-one bifurcation and stability analysis in an immunosuppressive infection model |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735110/ https://www.ncbi.nlm.nih.gov/pubmed/26877904 http://dx.doi.org/10.1186/s40064-016-1737-0 |
work_keys_str_mv | AT dadizohreh codimensiononebifurcationandstabilityanalysisinanimmunosuppressiveinfectionmodel AT alizadesamira codimensiononebifurcationandstabilityanalysisinanimmunosuppressiveinfectionmodel |