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Codimension-one bifurcation and stability analysis in an immunosuppressive infection model

One of the important medical problems is infectious diseases such as HIV and hepatitis which annually causes the death of many people. So it is important to study infectious diseases parametric models. In this paper, we investigate differential equations system of HIV and hepatitis (with delay and w...

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Autores principales: Dadi, Zohreh, Alizade, Samira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735110/
https://www.ncbi.nlm.nih.gov/pubmed/26877904
http://dx.doi.org/10.1186/s40064-016-1737-0
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author Dadi, Zohreh
Alizade, Samira
author_facet Dadi, Zohreh
Alizade, Samira
author_sort Dadi, Zohreh
collection PubMed
description One of the important medical problems is infectious diseases such as HIV and hepatitis which annually causes the death of many people. So it is important to study infectious diseases parametric models. In this paper, we investigate differential equations system of HIV and hepatitis (with delay and without delay) from the stability and codimension-one bifurcation point of view. We show that their dynamical behaviour will change when the parameters vary. We prove that this model has a saddle-node bifurcation and transcritical bifurcation when the delay parameter is absent. Also by using the center manifold theory, we show that the delay model has a saddle-node bifurcation.
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spelling pubmed-47351102016-02-12 Codimension-one bifurcation and stability analysis in an immunosuppressive infection model Dadi, Zohreh Alizade, Samira Springerplus Research One of the important medical problems is infectious diseases such as HIV and hepatitis which annually causes the death of many people. So it is important to study infectious diseases parametric models. In this paper, we investigate differential equations system of HIV and hepatitis (with delay and without delay) from the stability and codimension-one bifurcation point of view. We show that their dynamical behaviour will change when the parameters vary. We prove that this model has a saddle-node bifurcation and transcritical bifurcation when the delay parameter is absent. Also by using the center manifold theory, we show that the delay model has a saddle-node bifurcation. Springer International Publishing 2016-02-01 /pmc/articles/PMC4735110/ /pubmed/26877904 http://dx.doi.org/10.1186/s40064-016-1737-0 Text en © Dadi and Alizade. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research
Dadi, Zohreh
Alizade, Samira
Codimension-one bifurcation and stability analysis in an immunosuppressive infection model
title Codimension-one bifurcation and stability analysis in an immunosuppressive infection model
title_full Codimension-one bifurcation and stability analysis in an immunosuppressive infection model
title_fullStr Codimension-one bifurcation and stability analysis in an immunosuppressive infection model
title_full_unstemmed Codimension-one bifurcation and stability analysis in an immunosuppressive infection model
title_short Codimension-one bifurcation and stability analysis in an immunosuppressive infection model
title_sort codimension-one bifurcation and stability analysis in an immunosuppressive infection model
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735110/
https://www.ncbi.nlm.nih.gov/pubmed/26877904
http://dx.doi.org/10.1186/s40064-016-1737-0
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