Cargando…
School-based intervention for the prevention of HPV among adolescents: a cluster randomised controlled study
OBJECTIVE: To improve primary prevention of human papillomavirus (HPV) infection by promoting vaccination and increased condom use among upper secondary school students. DESIGN: Cluster randomised controlled trial. SETTING: 18 upper secondary schools in Sweden. PARTICIPANTS: Schools were first rando...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735203/ https://www.ncbi.nlm.nih.gov/pubmed/26817639 http://dx.doi.org/10.1136/bmjopen-2015-009875 |
_version_ | 1782413036547473408 |
---|---|
author | Grandahl, Maria Rosenblad, Andreas Stenhammar, Christina Tydén, Tanja Westerling, Ragnar Larsson, Margareta Oscarsson, Marie Andrae, Bengt Dalianis, Tina Nevéus, Tryggve |
author_facet | Grandahl, Maria Rosenblad, Andreas Stenhammar, Christina Tydén, Tanja Westerling, Ragnar Larsson, Margareta Oscarsson, Marie Andrae, Bengt Dalianis, Tina Nevéus, Tryggve |
author_sort | Grandahl, Maria |
collection | PubMed |
description | OBJECTIVE: To improve primary prevention of human papillomavirus (HPV) infection by promoting vaccination and increased condom use among upper secondary school students. DESIGN: Cluster randomised controlled trial. SETTING: 18 upper secondary schools in Sweden. PARTICIPANTS: Schools were first randomised to the intervention or the control group, after which individual classes were randomised so as to be included or not. Of the 832 students aged 16 years invited to participate during the regular individual health interview with the school nurse, 751 (90.2%) agreed to participate and 741 (89.1%) students completed the study. INTERVENTIONS: The intervention was based on the Health Belief Model (HBM). According to HBM, a person's health behaviour can be explained by individual beliefs regarding health actions. School nurses delivered 30 min face-to-face structured information about HPV, including cancer risks and HPV prevention, by propagating condom use and HPV vaccination. Students in the intervention and the control groups completed questionnaires at baseline and after 3 months. MAIN OUTCOME MEASURES: Intention to use condom with a new partner and beliefs about primary prevention of HPV, and also specifically vaccination status and increased condom use. RESULTS: All statistical analyses were performed at the individual level. The intervention had a significant effect on the intention to use condom (p=0.004). There was also a significant effect on HBM total score (p=0.003), with a 2.559 points higher score for the intervention group compared to the controls. The influence on the HBM parameters susceptibility and severity was also significant (p<0.001 for both variables). The intervention also influenced behaviour: girls in the intervention group chose to have themselves vaccinated to a significantly higher degree than the controls (p=0.02). No harms were reported. CONCLUSIONS: The school-based intervention had favourable effects on the beliefs about primary prevention of HPV, and increased the HPV vaccination rates in a diverse population of adolescents. TRIAL REGISTRATION NUMBER: NCT02280967; Results. |
format | Online Article Text |
id | pubmed-4735203 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-47352032016-02-09 School-based intervention for the prevention of HPV among adolescents: a cluster randomised controlled study Grandahl, Maria Rosenblad, Andreas Stenhammar, Christina Tydén, Tanja Westerling, Ragnar Larsson, Margareta Oscarsson, Marie Andrae, Bengt Dalianis, Tina Nevéus, Tryggve BMJ Open Public Health OBJECTIVE: To improve primary prevention of human papillomavirus (HPV) infection by promoting vaccination and increased condom use among upper secondary school students. DESIGN: Cluster randomised controlled trial. SETTING: 18 upper secondary schools in Sweden. PARTICIPANTS: Schools were first randomised to the intervention or the control group, after which individual classes were randomised so as to be included or not. Of the 832 students aged 16 years invited to participate during the regular individual health interview with the school nurse, 751 (90.2%) agreed to participate and 741 (89.1%) students completed the study. INTERVENTIONS: The intervention was based on the Health Belief Model (HBM). According to HBM, a person's health behaviour can be explained by individual beliefs regarding health actions. School nurses delivered 30 min face-to-face structured information about HPV, including cancer risks and HPV prevention, by propagating condom use and HPV vaccination. Students in the intervention and the control groups completed questionnaires at baseline and after 3 months. MAIN OUTCOME MEASURES: Intention to use condom with a new partner and beliefs about primary prevention of HPV, and also specifically vaccination status and increased condom use. RESULTS: All statistical analyses were performed at the individual level. The intervention had a significant effect on the intention to use condom (p=0.004). There was also a significant effect on HBM total score (p=0.003), with a 2.559 points higher score for the intervention group compared to the controls. The influence on the HBM parameters susceptibility and severity was also significant (p<0.001 for both variables). The intervention also influenced behaviour: girls in the intervention group chose to have themselves vaccinated to a significantly higher degree than the controls (p=0.02). No harms were reported. CONCLUSIONS: The school-based intervention had favourable effects on the beliefs about primary prevention of HPV, and increased the HPV vaccination rates in a diverse population of adolescents. TRIAL REGISTRATION NUMBER: NCT02280967; Results. BMJ Publishing Group 2016-01-27 /pmc/articles/PMC4735203/ /pubmed/26817639 http://dx.doi.org/10.1136/bmjopen-2015-009875 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Public Health Grandahl, Maria Rosenblad, Andreas Stenhammar, Christina Tydén, Tanja Westerling, Ragnar Larsson, Margareta Oscarsson, Marie Andrae, Bengt Dalianis, Tina Nevéus, Tryggve School-based intervention for the prevention of HPV among adolescents: a cluster randomised controlled study |
title | School-based intervention for the prevention of HPV among adolescents: a cluster randomised controlled study |
title_full | School-based intervention for the prevention of HPV among adolescents: a cluster randomised controlled study |
title_fullStr | School-based intervention for the prevention of HPV among adolescents: a cluster randomised controlled study |
title_full_unstemmed | School-based intervention for the prevention of HPV among adolescents: a cluster randomised controlled study |
title_short | School-based intervention for the prevention of HPV among adolescents: a cluster randomised controlled study |
title_sort | school-based intervention for the prevention of hpv among adolescents: a cluster randomised controlled study |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735203/ https://www.ncbi.nlm.nih.gov/pubmed/26817639 http://dx.doi.org/10.1136/bmjopen-2015-009875 |
work_keys_str_mv | AT grandahlmaria schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy AT rosenbladandreas schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy AT stenhammarchristina schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy AT tydentanja schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy AT westerlingragnar schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy AT larssonmargareta schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy AT oscarssonmarie schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy AT andraebengt schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy AT dalianistina schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy AT neveustryggve schoolbasedinterventionforthepreventionofhpvamongadolescentsaclusterrandomisedcontrolledstudy |