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Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy

Mitochondria are an essential source of ATP for cellular function, but when damaged, mitochondria generate a plethora of stress signals, which lead to cellular dysfunction and eventually programmed cell death. Thus, a major component of maintaining cellular homeostasis is the recognition and removal...

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Detalles Bibliográficos
Autores principales: Hamacher-Brady, Anne, Brady, Nathan Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735260/
https://www.ncbi.nlm.nih.gov/pubmed/26611876
http://dx.doi.org/10.1007/s00018-015-2087-8