ADAR1 Suppresses the Activation of Cytosolic RNA-Sensing Signaling Pathways to Protect the Liver from Ischemia/Reperfusion Injury

Excessive inflammation resulting from activation of the innate immune system significantly contributes to ischemia/reperfusion injury (IRI). Inflammatory reactions in both IRI and infections share the same signaling pathways evoked by danger/pathogen associated molecular pattern molecules. The cytos...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Wang, Guoliang, Zhang, Liyong, Zhang, Junbin, Zhang, Jinxiang, Wang, Qingde, Billiar, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735287/
https://www.ncbi.nlm.nih.gov/pubmed/26832817
http://dx.doi.org/10.1038/srep20248

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