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Virtual Nuclear Envelope Breakdown and Its Regulators in Fission Yeast Meiosis

Ran, a small GTPase, is required for the spindle formation and nuclear envelope (NE) formation. After NE breakdown (NEBD) during mitosis in metazoan cells, the Ran-GTP gradient across the NE is lost and Ran-GTP becomes concentrated around chromatin, thus affecting the stability of microtubules and p...

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Detalles Bibliográficos
Autores principales: Asakawa, Haruhiko, Yang, Hui-Ju, Hiraoka, Yasushi, Haraguchi, Tokuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735346/
https://www.ncbi.nlm.nih.gov/pubmed/26870731
http://dx.doi.org/10.3389/fcell.2016.00005