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Pharmacokinetic and Pharmacodynamic Integration and Modeling of Enrofloxacin in Swine for Escherichia coli

The aim of this study was to optimize the dose regimens of enrofloxacin to reduce the development of fluoroquinolone resistance in Escherichia coli (E.coli) using pharmacokinetic/pharmacodynamic (PK/PD) modeling approach. The single dose (2.5 mg/kg body weight) of enrofloxacin was administered intra...

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Detalles Bibliográficos
Autores principales:	Wang, Jianyi, Hao, Haihong, Huang, Lingli, Liu, Zhenli, Chen, Dongmei, Yuan, Zonghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735354/ https://www.ncbi.nlm.nih.gov/pubmed/26870006 http://dx.doi.org/10.3389/fmicb.2016.00036

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