Coordinated activation of distinct Ca(2+) sources and metabotropic glutamate receptors encodes Hebbian synaptic plasticity

At glutamatergic synapses, induction of associative synaptic plasticity requires time-correlated presynaptic and postsynaptic spikes to activate postsynaptic NMDA receptors (NMDARs). The magnitudes of the ensuing Ca(2+) transients within dendritic spines are thought to determine the amplitude and di...

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Detalles Bibliográficos
Autores principales: Tigaret, Cezar M., Olivo, Valeria, Sadowski, Josef H.L.P., Ashby, Michael C., Mellor, Jack R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735496/
https://www.ncbi.nlm.nih.gov/pubmed/26758963
http://dx.doi.org/10.1038/ncomms10289

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