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Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action

OBJECTIVE: Fibroblast growth factor 21 (FGF21) was recently discovered as stress-induced myokine during mitochondrial disease and proposed as key metabolic mediator of the integrated stress response (ISR) presumably causing systemic metabolic improvements. Curiously, the precise cell-non-autonomous...

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Detalles Bibliográficos
Autores principales:	Ost, Mario, Coleman, Verena, Voigt, Anja, van Schothorst, Evert M., Keipert, Susanne, van der Stelt, Inge, Ringel, Sebastian, Graja, Antonia, Ambrosi, Thomas, Kipp, Anna P., Jastroch, Martin, Schulz, Tim J., Keijer, Jaap, Klaus, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735627/ https://www.ncbi.nlm.nih.gov/pubmed/26909316 http://dx.doi.org/10.1016/j.molmet.2015.11.002

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