Cargando…

Ventromedial hypothalamic expression of Bdnf is required to establish normal patterns of afferent GABAergic connectivity and responses to hypoglycemia

OBJECTIVE: The ventromedial nucleus of the hypothalamus (VMH) controls energy and glucose homeostasis through direct connections to a distributed network of nuclei in the hypothalamus, midbrain, and hindbrain. Structural changes in VMH circuit morphology have the potential to alter VMH function thro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kamitakahara, Anna, Xu, Baoji, Simerly, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735662/ https://www.ncbi.nlm.nih.gov/pubmed/26909317 http://dx.doi.org/10.1016/j.molmet.2015.11.007

Ejemplares similares

Ventromedial Hypothalamic Nitric Oxide Production Is Necessary for Hypoglycemia Detection and Counterregulation
por: Fioramonti, Xavier, et al.
Publicado: (2010)

Brain-derived neurotrophic factor is required for axonal growth of selective groups of neurons in the arcuate nucleus
por: Liao, Guey-Ying, et al.
Publicado: (2015)

Ventromedial hypothalamic neurons control a defensive emotion state
por: Kunwar, Prabhat S, et al.
Publicado: (2015)

Estrogens modulate ventrolateral ventromedial hypothalamic glucose-inhibited neurons
por: Santiago, Ammy M., et al.
Publicado: (2016)

Norepinephrine Regulation of Ventromedial Hypothalamic Nucleus Astrocyte Glycogen Metabolism
por: Briski, Karen P., et al.
Publicado: (2021)

The ventromedial hypothalamic nucleus: watchdog of whole-body glucose homeostasis
por: Tu, Longlong, et al.
Publicado: (2022)

Ventrolateral ventromedial hypothalamic nucleus GABA neuron adaptation to recurring Hypoglycemia correlates with up-regulated 5′-AMP-activated protein kinase activity
por: Alhamyani, Abdulrahman, et al.
Publicado: (2021)

Hypoglycemia-Sensing Neurons of the Ventromedial Hypothalamus Require AMPK-Induced Txn2 Expression but Are Dispensable for Physiological Counterregulation
por: Quenneville, Simon, et al.
Publicado: (2020)

Hindbrain catecholamine regulation of ventromedial hypothalamic nucleus glycogen metabolism during acute versus recurring insulin-induced hypoglycemia in male versus female rat
por: Briski, K.P., et al.
Publicado: (2021)

Dynamic GABAergic afferent modulation of AgRP neurons
por: Garfield, Alastair S, et al.
Publicado: (2016)

Astrocytic BDNF signaling within the ventromedial hypothalamus regulates energy homeostasis
por: Ameroso, Dominique, et al.
Publicado: (2022)

Systemic Glucoregulation by Glucose-Sensing Neurons in the Ventromedial Hypothalamic Nucleus (VMH)
por: Shimazu, Takashi, et al.
Publicado: (2017)

Ventromedial hypothalamic OGT drives adipose tissue lipolysis and curbs obesity
por: Wang, Qi, et al.
Publicado: (2022)

BDNF Expression in Cortical GABAergic Interneurons
por: Tomás, Federico José Barreda, et al.
Publicado: (2020)

Diazepam Binding Inhibitor Control of Eu- and Hypoglycemic Patterns of Ventromedial Hypothalamic Nucleus Glucose-Regulatory Signaling
por: Roy, Sagor C., et al.
Publicado: (2023)

Modulation of β-Adrenergic Receptors in the Ventromedial Hypothalamus Influences Counterregulatory Responses to Hypoglycemia
por: Szepietowska, Barbara, et al.
Publicado: (2011)

Increased GABAergic Output in the Ventromedial Hypothalamus Contributes to Impaired Hypoglycemic Counterregulation in Diabetic Rats
por: Chan, Owen, et al.
Publicado: (2011)

HuD Interacts with Bdnf mRNA and Is Essential for Activity-Induced BDNF Synthesis in Dendrites
por: Vanevski, Filip, et al.
Publicado: (2015)

Ventromedial hypothalamic nucleus in regulation of stress-induced gastric mucosal injury in rats
por: Sun, Haiji, et al.
Publicado: (2018)

BDNF signaling and survival of striatal neurons
por: Baydyuk, Maryna, et al.
Publicado: (2014)

Dysbindin-1, BDNF, and GABAergic Transmission in Schizophrenia
por: Jun, Rachel, et al.
Publicado: (2022)

Amylin-Induced Central IL-6 Production Enhances Ventromedial Hypothalamic Leptin Signaling
por: Le Foll, Christelle, et al.
Publicado: (2015)

Distinct Neuronal Projections From the Hypothalamic Ventromedial Nucleus Mediate Glycemic and Behavioral Effects
por: Faber, Chelsea L., et al.
Publicado: (2018)

PACAP Neurons in the Ventromedial Hypothalamic Nucleus Are Glucose Inhibited and Their Selective Activation Induces Hyperglycaemia
por: Khodai, Tansi, et al.
Publicado: (2018)

Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity
por: Kim, Jung Dae, et al.
Publicado: (2017)

Populational heterogeneity and partial migratory origin of the ventromedial hypothalamic nucleus: genoarchitectonic analysis in the mouse
por: López-González, Lara, et al.
Publicado: (2023)

Lactate-Induced Release of GABA in the Ventromedial Hypothalamus Contributes to Counterregulatory Failure in Recurrent Hypoglycemia and Diabetes
por: Chan, Owen, et al.
Publicado: (2013)

Neurochemical properties of BDNF-containing neurons projecting to rostral ventromedial medulla in the ventrolateral periaqueductal gray
por: Yin, Jun-Bin, et al.
Publicado: (2014)

The Nutritional Induction of COUP-TFII Gene Expression in Ventromedial Hypothalamic Neurons Is Mediated by the Melanocortin Pathway
por: Sabra-Makke, Lina, et al.
Publicado: (2010)

Molecular and behavioral profiling of Dbx1-derived neurons in the arcuate, lateral and ventromedial hypothalamic nuclei
por: Sokolowski, Katie, et al.
Publicado: (2016)

Optogenetic activation of septal GABAergic afferents entrains neuronal firing in the medial habenula
por: Choi, Kyuhyun, et al.
Publicado: (2016)

GABAergic and Cortical and Subcortical Glutamatergic Axon Terminals Contain CB(1) Cannabinoid Receptors in the Ventromedial Nucleus of the Hypothalamus
por: Reguero, Leire, et al.
Publicado: (2011)

Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia
por: Tu, Longlong, et al.
Publicado: (2023)

Molecular and neural bases underlying roles of BDNF in the control of body weight
por: Vanevski, Filip, et al.
Publicado: (2013)

Afferent Connectivity of the Zebrafish Habenulae
por: Turner, Katherine J., et al.
Publicado: (2016)

Primary Afferent-Derived BDNF Contributes Minimally to the Processing of Pain and Itch
por: Dembo, Todd, et al.
Publicado: (2018)

Striatal Afferent BDNF Is Disrupted by Synucleinopathy and Partially Restored by STN DBS
por: Miller, Kathryn M., et al.
Publicado: (2021)

Lateral Hypothalamic GABAergic Neurons Encode and Potentiate Sucrose's Palatability
por: Garcia, Aketzali, et al.
Publicado: (2021)

Regulation of Satiety by Bdnf-e2-Expressing Neurons through TrkB Activation in Ventromedial Hypothalamus
por: Chu, Pengcheng, et al.
Publicado: (2023)

PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice
por: Saito, Kenji, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0e2avoeis1sj2lviul8tro0lik