The influence of genetic variants of sorafenib on clinical outcomes and toxic effects in patients with advanced renal cell carcinoma

The purpose of the present study was to investigate whether genetic variants that influence angiogenesis and sorafenib pharmacokinetics are associated with clinical outcomes and toxic effects in advanced renal cell carcinoma patients treated with this drug. One hundred patients with advanced renal c...

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Detalles Bibliográficos
Autores principales: Qin, Chao, Cao, Qiang, Li, Pu, Wang, Shangqian, Wang, Jian, Wang, Meilin, Chu, Haiyan, Zhou, Liqun, Li, Xuesong, Ye, Dingwei, Zhang, Hailiang, Huang, Yiran, Dong, Baijun, Sun, Xiaofeng, Zou, Qing, Cai, Hongzhou, Sun, Lijiang, Zhu, Jian, Liu, Fade, Ji, Junbiao, Cui, Li, Wang, Xiaoxiang, Zhou, Hai, Zhao, Hu, Wu, Bin, Chen, Jianchun, Jiang, Minjun, Zhang, Zhengdong, Shao, Pengfei, Ju, Xiaobing, Yin, Changjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735712/
https://www.ncbi.nlm.nih.gov/pubmed/26830973
http://dx.doi.org/10.1038/srep20089

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