Age-dependent inverse correlations in CSF and plasma amyloid-β(1–42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice

Amyloid-β (Aβ) plays a critical role as a biomarker in Alzheimer’s disease (AD) diagnosis. In addition to its diagnostic potential in the brain, recent studies have suggested that changes of Aβ level in the plasma can possibly indicate AD onset. In this study, we found that plasma Aβ(1–42) concentra...

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Detalles Bibliográficos
Autores principales: Cho, Soo Min, Lee, Sejin, Yang, Seung-Hoon, Kim, Hye Yun, Lee, Michael Jisoo, Kim, Hyunjin Vincent, Kim, Jiyoon, Baek, Seungyeop, Yun, Jin, Kim, Dohee, Kim, Yun Kyung, Cho, Yakdol, Woo, Jiwan, Kim, Tae Song, Kim, YoungSoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735736/
https://www.ncbi.nlm.nih.gov/pubmed/26830653
http://dx.doi.org/10.1038/srep20185

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