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Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy

Spinal muscular atrophy (SMA) is caused by low levels of survival motor neuron (SMN), a multifunctional protein essential for higher eukaryotes. While SMN is one of the most scrutinized proteins associated with neurodegeneration, its gender-specific role in vertebrates remains unknown. We utilized a...

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Detalles Bibliográficos
Autores principales:	Ottesen, Eric W., Howell, Matthew D., Singh, Natalia N., Seo, Joonbae, Whitley, Elizabeth M., Singh, Ravindra N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735745/ https://www.ncbi.nlm.nih.gov/pubmed/26830971 http://dx.doi.org/10.1038/srep20193

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