A universal probe design for colorimetric detection of single-nucleotide variation with visible readout and high specificity

Single-nucleotide variation (SNV) is a crucial biomarker for drug resistance-related detection in cancer and bacterial infection. However, the unintended binding of DNA probes limits the specificity of SNV detection, and the need for redesigned sequences compromise the universality of SNV assay. Her...

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Detalles Bibliográficos
Autores principales: Chen, Xueping, Zhou, Dandan, Shen, Huawei, Chen, Hui, Feng, Wenli, Xie, Guoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735751/
https://www.ncbi.nlm.nih.gov/pubmed/26830326
http://dx.doi.org/10.1038/srep20257

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