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Digital detection of endonuclease mediated gene disruption in the HIV provirus

Genome editing by designer nucleases is a rapidly evolving technology utilized in a highly diverse set of research fields. Among all fields, the T7 endonuclease mismatch cleavage assay, or Surveyor assay, is the most commonly used tool to assess genomic editing by designer nucleases. This assay, whi...

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Detalles Bibliográficos
Autores principales: Sedlak, Ruth Hall, Liang, Shu, Niyonzima, Nixon, De Silva Feelixge, Harshana S., Roychoudhury, Pavitra, Greninger, Alexander L., Weber, Nicholas D., Boissel, Sandrine, Scharenberg, Andrew M., Cheng, Anqi, Magaret, Amalia, Bumgarner, Roger, Stone, Daniel, Jerome, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735761/
https://www.ncbi.nlm.nih.gov/pubmed/26829887
http://dx.doi.org/10.1038/srep20064