Selection preserves Ubiquitin Specific Protease 4 alternative exon skipping in therian mammals

Ubiquitin specific protease 4 (USP4) is a highly networked deubiquitinating enzyme with reported roles in cancer, innate immunity and RNA splicing. In mammals it has two dominant isoforms arising from inclusion or skipping of exon 7 (E(7)). We evaluated two plausible mechanisms for the generation of...

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Detalles Bibliográficos
Autores principales: Vlasschaert, Caitlyn, Xia, Xuhua, Gray, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735762/
https://www.ncbi.nlm.nih.gov/pubmed/26833277
http://dx.doi.org/10.1038/srep20039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735762/
https://www.ncbi.nlm.nih.gov/pubmed/26833277
http://dx.doi.org/10.1038/srep20039

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