Cargando…
Selection preserves Ubiquitin Specific Protease 4 alternative exon skipping in therian mammals
Ubiquitin specific protease 4 (USP4) is a highly networked deubiquitinating enzyme with reported roles in cancer, innate immunity and RNA splicing. In mammals it has two dominant isoforms arising from inclusion or skipping of exon 7 (E(7)). We evaluated two plausible mechanisms for the generation of...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735762/ https://www.ncbi.nlm.nih.gov/pubmed/26833277 http://dx.doi.org/10.1038/srep20039 |