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Bacterial Muramyl Dipeptide (MDP) Restricts Human Cytomegalovirus Replication via an IFN-β-Dependent Pathway

We recently reported that induction of NOD2 by human Cytomegalovirus (HCMV) resulted in virus inhibition and upregulation of antiviral and inflammatory cytokines. Here we investigated the effects of muramyl dipeptide (MDP), a bacterial cell wall component that activates NOD2, on HCMV replication and...

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Detalles Bibliográficos
Autores principales:	Kapoor, Arun, Fan, Yi-Hsin, Arav-Boger, Ravit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735818/ https://www.ncbi.nlm.nih.gov/pubmed/26830977 http://dx.doi.org/10.1038/srep20295

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