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Longitudinal metabolic imaging of hepatocellular carcinoma in transgenic mouse models identifies acylcarnitine as a potential biomarker for early detection
The cumulative effects of hepatic injury due to hepatitis B virus (HBV) infections and aflatoxin-B(1) (AFB(1)) exposure are the major risk factors of HCC. Understanding early metabolic changes involving these risk factors in an animal model closely resembling human hepatocellular carcinoma (HCC) is...
Autores principales: | Yaligar, Jadegoud, Teoh, Wei Wei., Othman, Rashidah, Verma, Sanjay Kumar, Phang, Beng Hooi, Lee, Swee Shean, Wang, Who Whong, Toh, Han Chong, Gopalan, Venkatesh, Sabapathy, Kanaga, Velan, S. Sendhil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735819/ https://www.ncbi.nlm.nih.gov/pubmed/26831370 http://dx.doi.org/10.1038/srep20299 |
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