Knockin of Cre Gene at Ins2 Locus Reveals No Cre Activity in Mouse Hypothalamic Neurons

The recombination efficiency and cell specificity of Cre driver lines are critical for exploring pancreatic β cell biology with the Cre/LoxP approach. Some commonly used Cre lines are based on the short Ins2 promoter fragment and show recombination activity in hypothalamic neurons; however, whether...

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Detalles Bibliográficos
Autores principales: Li, Ling, Gao, Lin, Wang, Kejia, Ma, Xianhua, Chang, Xusheng, Shi, Jian-Hui, Zhang, Ye, Yin, Kai, Liu, Zhimin, Shi, Yuguang, Xie, Zhifang, Zhang, Weiping J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735843/
https://www.ncbi.nlm.nih.gov/pubmed/26830324
http://dx.doi.org/10.1038/srep20438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735843/
https://www.ncbi.nlm.nih.gov/pubmed/26830324
http://dx.doi.org/10.1038/srep20438

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