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Knockin of Cre Gene at Ins2 Locus Reveals No Cre Activity in Mouse Hypothalamic Neurons

The recombination efficiency and cell specificity of Cre driver lines are critical for exploring pancreatic β cell biology with the Cre/LoxP approach. Some commonly used Cre lines are based on the short Ins2 promoter fragment and show recombination activity in hypothalamic neurons; however, whether...

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Detalles Bibliográficos
Autores principales:	Li, Ling, Gao, Lin, Wang, Kejia, Ma, Xianhua, Chang, Xusheng, Shi, Jian-Hui, Zhang, Ye, Yin, Kai, Liu, Zhimin, Shi, Yuguang, Xie, Zhifang, Zhang, Weiping J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735843/ https://www.ncbi.nlm.nih.gov/pubmed/26830324 http://dx.doi.org/10.1038/srep20438

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