Leukotriene E(4) is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression

Leukotriene E(4) (LTE(4)) the most stable of the cysteinyl leukotrienes (cysLTs) binds poorly to classical type 1 (CysLT(1)) and 2 (CysLT(2)) receptors although it induces potent responses in human airways in vivo, such as bronchoconstriction, airway hyperresponsiveness and inflammatory cell influx...

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Detalles Bibliográficos
Autores principales: Foster, Holly R., Fuerst, Elisabeth, Branchett, William, Lee, Tak H., Cousins, David J., Woszczek, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735867/
https://www.ncbi.nlm.nih.gov/pubmed/26830450
http://dx.doi.org/10.1038/srep20461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735867/
https://www.ncbi.nlm.nih.gov/pubmed/26830450
http://dx.doi.org/10.1038/srep20461

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