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A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging

Introduction. Abdominal adhesions can cause serious morbidity and complicate subsequent operations. Their diagnosis is often one of exclusion due to a lack of a reliable, non-invasive diagnostic technique. Development and testing of a candidate technique are described below. Method. During respirati...

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Autores principales: Randall, David, Fenner, John, Gillott, Richard, ten Broek, Richard, Strik, Chema, Spencer, Paul, Bardhan, Karna Dev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735897/
https://www.ncbi.nlm.nih.gov/pubmed/26880884
http://dx.doi.org/10.1155/2016/2523768
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author Randall, David
Fenner, John
Gillott, Richard
ten Broek, Richard
Strik, Chema
Spencer, Paul
Bardhan, Karna Dev
author_facet Randall, David
Fenner, John
Gillott, Richard
ten Broek, Richard
Strik, Chema
Spencer, Paul
Bardhan, Karna Dev
author_sort Randall, David
collection PubMed
description Introduction. Abdominal adhesions can cause serious morbidity and complicate subsequent operations. Their diagnosis is often one of exclusion due to a lack of a reliable, non-invasive diagnostic technique. Development and testing of a candidate technique are described below. Method. During respiration, smooth visceral sliding motion occurs between the abdominal contents and the walls of the abdominal cavity. We describe a technique involving image segmentation and registration to calculate shear as an analogue for visceral slide based on the tracking of structures throughout the respiratory cycle. The presence of an adhesion is attributed to a resistance to visceral slide resulting in a discernible reduction in shear. The abdominal movement due to respiration is captured in sagittal dynamic MR images. Results. Clinical images were selected for analysis, including a patient with a surgically confirmed adhesion. Discernible reduction in shear was observed at the location of the adhesion while a consistent, gradually changing shear was observed in the healthy volunteers. Conclusion. The technique and its validation show encouraging results for adhesion detection but a larger study is now required to confirm its potential.
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spelling pubmed-47358972016-02-15 A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging Randall, David Fenner, John Gillott, Richard ten Broek, Richard Strik, Chema Spencer, Paul Bardhan, Karna Dev Gastroenterol Res Pract Research Article Introduction. Abdominal adhesions can cause serious morbidity and complicate subsequent operations. Their diagnosis is often one of exclusion due to a lack of a reliable, non-invasive diagnostic technique. Development and testing of a candidate technique are described below. Method. During respiration, smooth visceral sliding motion occurs between the abdominal contents and the walls of the abdominal cavity. We describe a technique involving image segmentation and registration to calculate shear as an analogue for visceral slide based on the tracking of structures throughout the respiratory cycle. The presence of an adhesion is attributed to a resistance to visceral slide resulting in a discernible reduction in shear. The abdominal movement due to respiration is captured in sagittal dynamic MR images. Results. Clinical images were selected for analysis, including a patient with a surgically confirmed adhesion. Discernible reduction in shear was observed at the location of the adhesion while a consistent, gradually changing shear was observed in the healthy volunteers. Conclusion. The technique and its validation show encouraging results for adhesion detection but a larger study is now required to confirm its potential. Hindawi Publishing Corporation 2016 2016-01-03 /pmc/articles/PMC4735897/ /pubmed/26880884 http://dx.doi.org/10.1155/2016/2523768 Text en Copyright © 2016 David Randall et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Randall, David
Fenner, John
Gillott, Richard
ten Broek, Richard
Strik, Chema
Spencer, Paul
Bardhan, Karna Dev
A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_full A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_fullStr A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_full_unstemmed A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_short A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging
title_sort novel diagnostic aid for detection of intra-abdominal adhesions to the anterior abdominal wall using dynamic magnetic resonance imaging
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735897/
https://www.ncbi.nlm.nih.gov/pubmed/26880884
http://dx.doi.org/10.1155/2016/2523768
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