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Bcl-xL promotes metastasis independent of its anti-apoptotic activity

Bcl-xL suppresses mitochondria-mediated apoptosis and is frequently overexpressed in cancer to promote cancer cell survival. Bcl-xL also promotes metastasis. However, it is unclear whether this metastatic function is dependent on its anti-apoptotic activity in the mitochondria. Here we demonstrate t...

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Detalles Bibliográficos
Autores principales:	Choi, Soyoung, Chen, Zhengming, Tang, Laura H., Fang, Yuanzhang, Shin, Sandra J., Panarelli, Nicole C., Chen, Yao-Tseng, Li, Yi, Jiang, Xuejun, Du, Yi-Chieh Nancy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735924/ https://www.ncbi.nlm.nih.gov/pubmed/26785948 http://dx.doi.org/10.1038/ncomms10384

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