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Analgesic Effect of Intra-Articular Injection of Temperature-Responsive Hydrogel Containing Bupivacaine on Osteoarthritic Pain in Rats

The present study examined the analgesic effects of slow-releasing bupivacaine from hydrogel on chronic arthritic pain in rats. Osteoarthritis (OA) was induced by monosodium iodoacetate (MIA) injection into the right knee joint. Hydrogel (HG: 20, 30, and 50 μL) and temperature-sensitive hydrogel con...

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Detalles Bibliográficos
Autores principales:	Kim, Taemin, Seol, Dong Rim, Hahm, Suk-Chan, Ko, Cheolwoong, Kim, Eun-Hye, Chun, Keyoungjin, Kim, Junesun, Lim, Tae-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735994/ https://www.ncbi.nlm.nih.gov/pubmed/26881207 http://dx.doi.org/10.1155/2015/812949

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