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Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue
BACKGROUND: Using hair samples to analyze the trace element concentrations is of interest among many researchers. X-ray fluorescence (XRF) and X-ray diffraction (XRD) are the most common methods in studying the structure and concentration of elements of tissues and also crystalline materials, using...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shahid Beheshti University of Medical Sciences
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736071/ https://www.ncbi.nlm.nih.gov/pubmed/26855721 http://dx.doi.org/10.17795/ijcp-3983 |
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author | Maziar, Asghar Shahbazi-Gahrouei, Daryoush Tavakoli, Mohammad Bagher Changizi, Vahid |
author_facet | Maziar, Asghar Shahbazi-Gahrouei, Daryoush Tavakoli, Mohammad Bagher Changizi, Vahid |
author_sort | Maziar, Asghar |
collection | PubMed |
description | BACKGROUND: Using hair samples to analyze the trace element concentrations is of interest among many researchers. X-ray fluorescence (XRF) and X-ray diffraction (XRD) are the most common methods in studying the structure and concentration of elements of tissues and also crystalline materials, using low energy X-ray. OBJECTIVES: In the present study, the detection ability of Wave Length X-ray Fluorescence (WLXRF) of breast cancer at early stages was evaluated and the results were compared with other routine modalities such as mammography. MATERIALS AND METHODS: Hair samples of 54 women (including 27 healthy and 27 patients) with average age of 52.03 ± 11.44 years were analyzed. All the sample donors were Iranian women. For the measurements Wave Length X-ray Fluorescence (WLXRF) method was used. RESULTS: Trace elements in healthy individuals were higher than those in cancer patients. In addition, sensitivity of the used method (WLXRF) was 96% compared to mammography (77%) as a gold standard for breast cancer detection. CONCLUSIONS: Trace elements in healthy individuals were higher than cancer patients and it seems that WLXRF may be used as a safe, low cost and reliable method with sensitivity higher than those of the other two relevant methods, XRD and mammography. |
format | Online Article Text |
id | pubmed-4736071 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Shahid Beheshti University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-47360712016-02-05 Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue Maziar, Asghar Shahbazi-Gahrouei, Daryoush Tavakoli, Mohammad Bagher Changizi, Vahid Iran J Cancer Prev Research Article BACKGROUND: Using hair samples to analyze the trace element concentrations is of interest among many researchers. X-ray fluorescence (XRF) and X-ray diffraction (XRD) are the most common methods in studying the structure and concentration of elements of tissues and also crystalline materials, using low energy X-ray. OBJECTIVES: In the present study, the detection ability of Wave Length X-ray Fluorescence (WLXRF) of breast cancer at early stages was evaluated and the results were compared with other routine modalities such as mammography. MATERIALS AND METHODS: Hair samples of 54 women (including 27 healthy and 27 patients) with average age of 52.03 ± 11.44 years were analyzed. All the sample donors were Iranian women. For the measurements Wave Length X-ray Fluorescence (WLXRF) method was used. RESULTS: Trace elements in healthy individuals were higher than those in cancer patients. In addition, sensitivity of the used method (WLXRF) was 96% compared to mammography (77%) as a gold standard for breast cancer detection. CONCLUSIONS: Trace elements in healthy individuals were higher than cancer patients and it seems that WLXRF may be used as a safe, low cost and reliable method with sensitivity higher than those of the other two relevant methods, XRD and mammography. Shahid Beheshti University of Medical Sciences 2015-12-23 2015-12 /pmc/articles/PMC4736071/ /pubmed/26855721 http://dx.doi.org/10.17795/ijcp-3983 Text en Copyright © 2015, Iranian Journal of Cancer Prevention. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. |
spellingShingle | Research Article Maziar, Asghar Shahbazi-Gahrouei, Daryoush Tavakoli, Mohammad Bagher Changizi, Vahid Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue |
title | Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue |
title_full | Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue |
title_fullStr | Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue |
title_full_unstemmed | Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue |
title_short | Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue |
title_sort | non invasive xrf analysis of human hair for health state determination of breast tissue |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736071/ https://www.ncbi.nlm.nih.gov/pubmed/26855721 http://dx.doi.org/10.17795/ijcp-3983 |
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