Evidence for Detrimental Cross Interactions between Reactive Oxygen and Nitrogen Species in Leber's Hereditary Optic Neuropathy Cells

Here we have collected evidence suggesting that chronic changes in the NO homeostasis and the rise of reactive oxygen species bioavailability can contribute to cell dysfunction in Leber's hereditary optic neuropathy (LHON) patients. We report that peripheral blood mononuclear cells (PBMCs), der...

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Detalles Bibliográficos
Autores principales: Falabella, Micol, Forte, Elena, Magnifico, Maria Chiara, Santini, Paolo, Arese, Marzia, Giuffrè, Alessandro, Radić, Kristina, Chessa, Luciana, Coarelli, Giulia, Buscarinu, Maria Chiara, Mechelli, Rosella, Salvetti, Marco, Sarti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736215/
https://www.ncbi.nlm.nih.gov/pubmed/26881022
http://dx.doi.org/10.1155/2016/3187560

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