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RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis
BACKGROUND: Regulator of G-protein signaling (RGS) family proteins, which are GTPase accelerating proteins (GAPs) that negatively regulate G-protein-coupled receptors (GPCRs), are known to be important modulators of immune cell activation and function. Various single-nucleotide polymorphisms in RGS...
Autores principales: | Lee, Jae-Kyung, Kannarkat, George T., Chung, Jaegwon, Joon Lee, Hyun, Graham, Kareem L., Tansey, Malú G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736282/ https://www.ncbi.nlm.nih.gov/pubmed/26831924 http://dx.doi.org/10.1186/s12974-016-0491-0 |
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