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Two-stage Genome-wide Methylation Profiling in Childhood-onset Crohn's Disease Implicates Epigenetic Alterations at the VMP1/MIR21 and HLA Loci

BACKGROUND: As a result of technological and analytical advances, genome-wide characterization of key epigenetic alterations is now feasible in complex diseases. We hypothesized that this may provide important insights into gene-environmental interactions in Crohn's disease (CD) and is especial...

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Detalles Bibliográficos
Autores principales:	Adams, Alex T., Kennedy, Nicholas A., Hansen, Richard, Ventham, Nicholas T., O'Leary, Kate R., Drummond, Hazel E., Noble, Colin L., El-Omar, Emad, Russell, Richard K., Wilson, David C., Nimmo, Elaine R., Hold, Georgina L., Satsangi, Jack
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2014
Materias:	Original Basic Science Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736293/ https://www.ncbi.nlm.nih.gov/pubmed/25144570 http://dx.doi.org/10.1097/MIB.0000000000000179

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