Pharmacological Inhibition of Gal-3 in Mesenchymal Stem Cells Enhances Their Capacity to Promote Alternative Activation of Macrophages in Dextran Sulphate Sodium-Induced Colitis

Transplantation of mesenchymal stem cells (MSCs) reduces the severity of dextran sulphate sodium- (DSS-) induced colitis. MSCs are able to secrete Galectin-3 (Gal-3), a protein known to affect proliferation, adhesion, and migration of immune cells. We investigate whether newly synthetized inhibitor...

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Detalles Bibliográficos
Autores principales: Simovic Markovic, Bojana, Nikolic, Aleksandar, Gazdic, Marina, Nurkovic, Jasmin, Djordjevic, Irena, Arsenijevic, Nebojsa, Stojkovic, Miodrag, Lukic, Miodrag L., Volarevic, Vladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736319/
https://www.ncbi.nlm.nih.gov/pubmed/27057168
http://dx.doi.org/10.1155/2016/2640746

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