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TLR4 Signaling in MPP(+)-Induced Activation of BV-2 Cells

Aims. This work was conducted to establish an in vitro Parkinson's disease (PD) model by exposing BV-2 cells to 1-methyl-4-phenylpyridinium (MPP(+)) and exploring the roles of TLR2/TLR4/TLR9 in inflammatory responses to MPP(+). Methods/Results. MTT assay showed that cell viability of BV-2 cells...

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Detalles Bibliográficos
Autores principales: Zhou, Peng, Weng, Ruihui, Chen, Zhaoyu, Wang, Rui, Zou, Jing, Liu, Xu, Liao, Jinchi, Wang, Yanping, Xia, Ying, Wang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736374/
https://www.ncbi.nlm.nih.gov/pubmed/26881113
http://dx.doi.org/10.1155/2016/5076740