Cargando…

iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study

Phototransduction is accomplished in the retina by photoreceptor neurons and retinal pigment epithelium (RPE) cells. Photoreceptors rely heavily on the RPE, and death or dysfunction of RPE is characteristic of age-related macular degeneration (AMD), a very common neurodegenerative disease for which...

Descripción completa

Detalles Bibliográficos
Autores principales:	Westenskow, Peter D., Bucher, Felicitas, Bravo, Stephen, Kurihara, Toshihide, Feitelberg, Daniel, Paris, Liliana P., Aguilar, Edith, Lin, Jonathan H., Friedlander, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736415/ https://www.ncbi.nlm.nih.gov/pubmed/26880994 http://dx.doi.org/10.1155/2016/8470263

Ejemplares similares

Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models
por: Sugita, Sunao, et al.
Publicado: (2017)

Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration
por: Kurihara, Toshihide, et al.
Publicado: (2016)

Pigment Epithelium-Derived Factor Secreted from Retinal Pigment Epithelium Facilitates Apoptotic Cell Death of iPSC
por: Kanemura, Hoshimi, et al.
Publicado: (2013)

iPSC-MSCs and islet allograft tolerance
por: Wang, Tong-Song, et al.
Publicado: (2015)

Cell-autonomous lipid-handling defects in Stargardt iPSC-derived retinal pigment epithelium cells
por: Farnoodian, Mitra, et al.
Publicado: (2022)

Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons
por: Cook, Sophie R., et al.
Publicado: (2020)

Impaired Mitochondrial Function in iPSC-Retinal Pigment Epithelium with the Complement Factor H Polymorphism for Age-Related Macular Degeneration
por: Ebeling, Mara C., et al.
Publicado: (2021)

Human iPSC-Derived Retinal Organoids and Retinal Pigment Epithelium for Novel Intronic RPGR Variant Assessment for Therapy Suitability
por: Chahine Karam, Fidelle, et al.
Publicado: (2022)

Proof of concept for AAV2/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient
por: Cereso, Nicolas, et al.
Publicado: (2014)

Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells
por: Schwarz, Nele, et al.
Publicado: (2015)

Global metabolomics reveals metabolic dysregulation in ischemic retinopathy
por: Paris, Liliana P., et al.
Publicado: (2015)

Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye
por: Kurihara, Toshihide, et al.
Publicado: (2011)

Tumorigenicity Studies of Induced Pluripotent Stem Cell (iPSC)-Derived Retinal Pigment Epithelium (RPE) for the Treatment of Age-Related Macular Degeneration
por: Kanemura, Hoshimi, et al.
Publicado: (2014)

Human iPSC-Derived Retinal Pigment Epithelium: A Model System for Prioritizing and Functionally Characterizing Causal Variants at AMD Risk Loci
por: Smith, Erin N., et al.
Publicado: (2019)

Oxidative stress differentially impacts apical and basolateral secretion of angiogenic factors from human iPSC-derived retinal pigment epithelium cells
por: Chen, Lisheng, et al.
Publicado: (2022)

iPSC–derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function
por: Eade, Kevin T., et al.
Publicado: (2023)

Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD
por: Gleeson, John P., et al.
Publicado: (2020)

Human iPSC- and Primary-Retinal Pigment Epithelial Cells for Modeling Age-Related Macular Degeneration
por: Fisher, Cody R., et al.
Publicado: (2022)

iPSC-Derived Regulatory Dendritic Cells Inhibit Allograft Rejection by Generating Alloantigen-Specific Regulatory T Cells
por: Cai, Songjie, et al.
Publicado: (2017)

Banking on iPSC- Is it Doable and is it Worthwhile
por: Solomon, Susan, et al.
Publicado: (2014)

Roadblocks in the Path of iPSC to the Clinic
por: Garreta, Elena, et al.
Publicado: (2018)

iPSC Bioprinting: Where are We at?
por: Romanazzo, Sara, et al.
Publicado: (2019)

Maturing iPSC-Derived Cardiomyocytes
por: Tang, Bor Luen
Publicado: (2020)

iPSC for modeling neurodegenerative disorders
por: Valadez-Barba, Valeria, et al.
Publicado: (2020)

Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors
por: Sugita, Sunao, et al.
Publicado: (2016)

Modeling of mitochondrial bioenergetics and autophagy impairment in MELAS-mutant iPSC-derived retinal pigment epithelial cells
por: Bhattacharya, Sujoy, et al.
Publicado: (2022)

Pro-maturational Effects of Human iPSC-Derived Cortical Astrocytes upon iPSC-Derived Cortical Neurons
por: Hedegaard, Anne, et al.
Publicado: (2020)

Cell-Type-Specific Adhesiveness and Proliferation Propensity on Laminin Isoforms Enable Purification of iPSC-Derived Corneal Epithelium
por: Shibata, Shun, et al.
Publicado: (2020)

SARS-CoV-2 induces barrier damage and inflammatory responses in the human iPSC-derived intestinal epithelium
por: Yamada, Shigeru, et al.
Publicado: (2022)

The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC-derived cardiomyocytes
por: Necela, Brian M., et al.
Publicado: (2017)

iPSC-based model of viral infection
Publicado: (2012)

Chromatin looping is needed for iPSC induction
por: Hu, Ji-Fan, et al.
Publicado: (2014)

Human iPSC banking: barriers and opportunities
por: Huang, Ching-Ying, et al.
Publicado: (2019)

Application of iPSC to Modelling of Respiratory Diseases
por: Calvert, Ben A., et al.
Publicado: (2020)

The Utilisation of Hydrogels for iPSC-Cardiomyocyte Research
por: Patel, Leena, et al.
Publicado: (2023)

Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill
por: González, Alfredo, et al.
Publicado: (2004)

Generation of iPSC-Derived Human Peripheral Sensory Neurons Releasing Substance P Elicited by TRPV1 Agonists
por: Guimarães, Marília Z. P., et al.
Publicado: (2018)

Tubuloid culture enables long-term expansion of functional human kidney tubule epithelium from iPSC-derived organoids
por: Yousef Yengej, Fjodor A., et al.
Publicado: (2023)

Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons
por: Magliocca, Valentina, et al.
Publicado: (2017)

Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors
por: Ghila, Luiza, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5oqa7m1do7v146vee556lg5ngf