Cargando…
Optical Control of Insulin Secretion Using an Incretin Switch
Incretin mimetics are set to become a mainstay of type 2 diabetes treatment. By acting on the pancreas and brain, they potentiate insulin secretion and induce weight loss to preserve normoglycemia. Despite this, incretin therapy has been associated with off‐target effects, including nausea and gastr...
Autores principales: | Broichhagen, Johannes, Podewin, Tom, Meyer‐Berg, Helena, von Ohlen, Yorrick, Johnston, Natalie R., Jones, Ben J., Bloom, Stephen R., Rutter, Guy A., Hoffmann‐Röder, Anja, Hodson, David J., Trauner, Dirk |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY‐VCH Verlag
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736448/ https://www.ncbi.nlm.nih.gov/pubmed/26585495 http://dx.doi.org/10.1002/anie.201506384 |
Ejemplares similares
-
Allosteric Optical Control of a Class B G‐Protein‐Coupled Receptor
por: Broichhagen, Johannes, et al.
Publicado: (2016) -
Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone
por: Podewin, Tom, et al.
Publicado: (2017) -
Remote control of glucose homeostasis in vivo using photopharmacology
por: Mehta, Zenobia B., et al.
Publicado: (2017) -
Incretin-Modulated Beta Cell Energetics in Intact Islets of Langerhans
por: Hodson, David J., et al.
Publicado: (2014) -
Conditional and Reversible Activation of Class A and
B G Protein-Coupled Receptors Using Tethered Pharmacology
por: Podewin, Tom, et al.
Publicado: (2018)