Enantioselective Diamination with Novel Chiral Hypervalent Iodine Catalysts

Vicinal diamines constitute one the most important functional motif in organic chemistry because of its wide occurrence in a variety of biological and pharmaceutical molecules. We report an efficient metal‐free, highly stereoselective intramolecular diamination using a novel chiral hypervalent iodin...

Descripción completa

Detalles Bibliográficos
Autores principales: Mizar, Pushpak, Laverny, Aragorn, El‐Sherbini, Mohammad, Farid, Umar, Brown, Michael, Malmedy, Florence, Wirth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736455/
https://www.ncbi.nlm.nih.gov/pubmed/25042733
http://dx.doi.org/10.1002/chem.201403891
_version_ 1782413287809351680
author Mizar, Pushpak
Laverny, Aragorn
El‐Sherbini, Mohammad
Farid, Umar
Brown, Michael
Malmedy, Florence
Wirth, Thomas
author_facet Mizar, Pushpak
Laverny, Aragorn
El‐Sherbini, Mohammad
Farid, Umar
Brown, Michael
Malmedy, Florence
Wirth, Thomas
author_sort Mizar, Pushpak
collection PubMed
description Vicinal diamines constitute one the most important functional motif in organic chemistry because of its wide occurrence in a variety of biological and pharmaceutical molecules. We report an efficient metal‐free, highly stereoselective intramolecular diamination using a novel chiral hypervalent iodine reagent together with its application as an efficient catalyst for the synthesis of diamines.
format Online
Article
Text
id pubmed-4736455
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher WILEY‐VCH Verlag
record_format MEDLINE/PubMed
spelling pubmed-47364552016-02-11 Enantioselective Diamination with Novel Chiral Hypervalent Iodine Catalysts Mizar, Pushpak Laverny, Aragorn El‐Sherbini, Mohammad Farid, Umar Brown, Michael Malmedy, Florence Wirth, Thomas Chemistry Communications Vicinal diamines constitute one the most important functional motif in organic chemistry because of its wide occurrence in a variety of biological and pharmaceutical molecules. We report an efficient metal‐free, highly stereoselective intramolecular diamination using a novel chiral hypervalent iodine reagent together with its application as an efficient catalyst for the synthesis of diamines. WILEY‐VCH Verlag 2014-07-17 2014-08-04 /pmc/articles/PMC4736455/ /pubmed/25042733 http://dx.doi.org/10.1002/chem.201403891 Text en © 2014 The Authors. Published by Wiley‐VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Open access.
spellingShingle Communications
Mizar, Pushpak
Laverny, Aragorn
El‐Sherbini, Mohammad
Farid, Umar
Brown, Michael
Malmedy, Florence
Wirth, Thomas
Enantioselective Diamination with Novel Chiral Hypervalent Iodine Catalysts
title Enantioselective Diamination with Novel Chiral Hypervalent Iodine Catalysts
title_full Enantioselective Diamination with Novel Chiral Hypervalent Iodine Catalysts
title_fullStr Enantioselective Diamination with Novel Chiral Hypervalent Iodine Catalysts
title_full_unstemmed Enantioselective Diamination with Novel Chiral Hypervalent Iodine Catalysts
title_short Enantioselective Diamination with Novel Chiral Hypervalent Iodine Catalysts
title_sort enantioselective diamination with novel chiral hypervalent iodine catalysts
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736455/
https://www.ncbi.nlm.nih.gov/pubmed/25042733
http://dx.doi.org/10.1002/chem.201403891
work_keys_str_mv AT mizarpushpak enantioselectivediaminationwithnovelchiralhypervalentiodinecatalysts
AT lavernyaragorn enantioselectivediaminationwithnovelchiralhypervalentiodinecatalysts
AT elsherbinimohammad enantioselectivediaminationwithnovelchiralhypervalentiodinecatalysts
AT faridumar enantioselectivediaminationwithnovelchiralhypervalentiodinecatalysts
AT brownmichael enantioselectivediaminationwithnovelchiralhypervalentiodinecatalysts
AT malmedyflorence enantioselectivediaminationwithnovelchiralhypervalentiodinecatalysts
AT wirththomas enantioselectivediaminationwithnovelchiralhypervalentiodinecatalysts

Ejemplares similares