Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok

We report a case of several autoimmune disorders eventually presenting as severe multi organ dysfunction syndrome caused by adult hemophagocytic lymphohistiocytosis (HLH). Clinical and laboratory tests might lead to fatal misinterpretation without awareness of its diagnostic evaluation, as HLH share...

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Detalles Bibliográficos
Autores principales: Fleischmann, Robert, Böhmerle, Wolfgang, von Laffert, Maximilian, Jöhrens, Korinna, Mengel, Annerose, Hotter, Benjamin, Lindenberg, Robert, Scheibe, Franziska, Köhnlein, Martin, von Bahr Greenwood, Tatiana, Henter, Jan Inge, Meisel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736532/
https://www.ncbi.nlm.nih.gov/pubmed/26862416
http://dx.doi.org/10.1002/ccr3.467
Descripción
Sumario:We report a case of several autoimmune disorders eventually presenting as severe multi organ dysfunction syndrome caused by adult hemophagocytic lymphohistiocytosis (HLH). Clinical and laboratory tests might lead to fatal misinterpretation without awareness of its diagnostic evaluation, as HLH shares common features with sepsis and immune‐mediated systemic inflammatory response syndromes.

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