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Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok
We report a case of several autoimmune disorders eventually presenting as severe multi organ dysfunction syndrome caused by adult hemophagocytic lymphohistiocytosis (HLH). Clinical and laboratory tests might lead to fatal misinterpretation without awareness of its diagnostic evaluation, as HLH share...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736532/ https://www.ncbi.nlm.nih.gov/pubmed/26862416 http://dx.doi.org/10.1002/ccr3.467 |
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author | Fleischmann, Robert Böhmerle, Wolfgang von Laffert, Maximilian Jöhrens, Korinna Mengel, Annerose Hotter, Benjamin Lindenberg, Robert Scheibe, Franziska Köhnlein, Martin von Bahr Greenwood, Tatiana Henter, Jan Inge Meisel, Andreas |
author_facet | Fleischmann, Robert Böhmerle, Wolfgang von Laffert, Maximilian Jöhrens, Korinna Mengel, Annerose Hotter, Benjamin Lindenberg, Robert Scheibe, Franziska Köhnlein, Martin von Bahr Greenwood, Tatiana Henter, Jan Inge Meisel, Andreas |
author_sort | Fleischmann, Robert |
collection | PubMed |
description | We report a case of several autoimmune disorders eventually presenting as severe multi organ dysfunction syndrome caused by adult hemophagocytic lymphohistiocytosis (HLH). Clinical and laboratory tests might lead to fatal misinterpretation without awareness of its diagnostic evaluation, as HLH shares common features with sepsis and immune‐mediated systemic inflammatory response syndromes. |
format | Online Article Text |
id | pubmed-4736532 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-47365322016-02-09 Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok Fleischmann, Robert Böhmerle, Wolfgang von Laffert, Maximilian Jöhrens, Korinna Mengel, Annerose Hotter, Benjamin Lindenberg, Robert Scheibe, Franziska Köhnlein, Martin von Bahr Greenwood, Tatiana Henter, Jan Inge Meisel, Andreas Clin Case Rep Case Reports We report a case of several autoimmune disorders eventually presenting as severe multi organ dysfunction syndrome caused by adult hemophagocytic lymphohistiocytosis (HLH). Clinical and laboratory tests might lead to fatal misinterpretation without awareness of its diagnostic evaluation, as HLH shares common features with sepsis and immune‐mediated systemic inflammatory response syndromes. John Wiley and Sons Inc. 2015-12-16 /pmc/articles/PMC4736532/ /pubmed/26862416 http://dx.doi.org/10.1002/ccr3.467 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Reports Fleischmann, Robert Böhmerle, Wolfgang von Laffert, Maximilian Jöhrens, Korinna Mengel, Annerose Hotter, Benjamin Lindenberg, Robert Scheibe, Franziska Köhnlein, Martin von Bahr Greenwood, Tatiana Henter, Jan Inge Meisel, Andreas Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok |
title | Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok |
title_full | Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok |
title_fullStr | Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok |
title_full_unstemmed | Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok |
title_short | Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok |
title_sort | adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736532/ https://www.ncbi.nlm.nih.gov/pubmed/26862416 http://dx.doi.org/10.1002/ccr3.467 |
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