Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer

Drug–Drug interactions is important when caring for warfarin‐treated patients. We examined the impact on INR with coadministration of warfarin and caspofungin and showed no affect on the INR. Coadministrations of fluconazole lead to a marked increase in INR. We concluded that administration of caspo...

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Detalles Bibliográficos
Autores principales: Vedtofte, Thomas, Thisted, Camilla Heyn, Friis‐Hansen, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736535/
https://www.ncbi.nlm.nih.gov/pubmed/26862410
http://dx.doi.org/10.1002/ccr3.469
Descripción
Sumario:Drug–Drug interactions is important when caring for warfarin‐treated patients. We examined the impact on INR with coadministration of warfarin and caspofungin and showed no affect on the INR. Coadministrations of fluconazole lead to a marked increase in INR. We concluded that administration of caspofungin and warfarin was safe.

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