Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer

Drug–Drug interactions is important when caring for warfarin‐treated patients. We examined the impact on INR with coadministration of warfarin and caspofungin and showed no affect on the INR. Coadministrations of fluconazole lead to a marked increase in INR. We concluded that administration of caspo...

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Detalles Bibliográficos
Autores principales: Vedtofte, Thomas, Thisted, Camilla Heyn, Friis‐Hansen, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736535/
https://www.ncbi.nlm.nih.gov/pubmed/26862410
http://dx.doi.org/10.1002/ccr3.469
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author Vedtofte, Thomas
Thisted, Camilla Heyn
Friis‐Hansen, Lennart
author_facet Vedtofte, Thomas
Thisted, Camilla Heyn
Friis‐Hansen, Lennart
author_sort Vedtofte, Thomas
collection PubMed
description Drug–Drug interactions is important when caring for warfarin‐treated patients. We examined the impact on INR with coadministration of warfarin and caspofungin and showed no affect on the INR. Coadministrations of fluconazole lead to a marked increase in INR. We concluded that administration of caspofungin and warfarin was safe.
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spelling pubmed-47365352016-02-09 Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer Vedtofte, Thomas Thisted, Camilla Heyn Friis‐Hansen, Lennart Clin Case Rep Case Reports Drug–Drug interactions is important when caring for warfarin‐treated patients. We examined the impact on INR with coadministration of warfarin and caspofungin and showed no affect on the INR. Coadministrations of fluconazole lead to a marked increase in INR. We concluded that administration of caspofungin and warfarin was safe. John Wiley and Sons Inc. 2015-12-09 /pmc/articles/PMC4736535/ /pubmed/26862410 http://dx.doi.org/10.1002/ccr3.469 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Vedtofte, Thomas
Thisted, Camilla Heyn
Friis‐Hansen, Lennart
Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer
title Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer
title_full Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer
title_fullStr Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer
title_full_unstemmed Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer
title_short Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer
title_sort warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736535/
https://www.ncbi.nlm.nih.gov/pubmed/26862410
http://dx.doi.org/10.1002/ccr3.469
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AT friishansenlennart warfarintreatmentandantifungalagentcaspofunginforseverefungalinfectioninapatientpreviouslytreatedwithradiotherapyfororopharyngealcancer

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