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Treatment with a Monoclonal Anti-IL-12p40 Antibody Induces Substantial Gut Microbiota Changes in an Experimental Colitis Model

Background and Aim. Crohn's disease is associated with gut microbiota (GM) dysbiosis. Treatment with the anti-IL-12p40 monoclonal antibody (12p40-mAb) has therapeutic effect in Crohn's disease patients. This study addresses whether a 12p40-mAb treatment influences gut microbiota (GM) compo...

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Detalles Bibliográficos
Autores principales:	Castro-Mejía, Josué, Jakesevic, Maja, Krych, Łukasz, Nielsen, Dennis S., Hansen, Lars H., Sondergaard, Bodil C., Kvist, Peter H., Hansen, Axel K., Holm, Thomas L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736578/ https://www.ncbi.nlm.nih.gov/pubmed/26880890 http://dx.doi.org/10.1155/2016/4953120

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