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DNA methylation profiling of primary neuroblastoma tumors using methyl-CpG-binding domain sequencing

Comprehensive genome-wide DNA methylation studies in neuroblastoma (NB), a childhood tumor that originates from precursor cells of the sympathetic nervous system, are scarce. Recently, we profiled the DNA methylome of 102 well-annotated primary NB tumors by methyl-CpG-binding domain (MBD) sequencing...

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Detalles Bibliográficos
Autores principales: Decock, Anneleen, Ongenaert, Maté, Van Criekinge, Wim, Speleman, Frank, Vandesompele, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736656/
https://www.ncbi.nlm.nih.gov/pubmed/26836295
http://dx.doi.org/10.1038/sdata.2016.4