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ICOS is required for the generation of both central and effector CD4(+) memory T‐cell populations following acute bacterial infection
Interactions between ICOS and ICOS ligand (ICOSL) are essential for the development of T follicular helper (Tfh) cells and thus the formation and maintenance of GC reactions. Given the conflicting reports on the requirement of other CD4(+) T‐cell populations for ICOS signals, we have employed a rang...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736665/ https://www.ncbi.nlm.nih.gov/pubmed/25754933 http://dx.doi.org/10.1002/eji.201445421 |