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ICOS is required for the generation of both central and effector CD4(+) memory T‐cell populations following acute bacterial infection

Interactions between ICOS and ICOS ligand (ICOSL) are essential for the development of T follicular helper (Tfh) cells and thus the formation and maintenance of GC reactions. Given the conflicting reports on the requirement of other CD4(+) T‐cell populations for ICOS signals, we have employed a rang...

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Detalles Bibliográficos
Autores principales: Marriott, Clare L., Carlesso, Gianluca, Herbst, Ronald, Withers, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736665/
https://www.ncbi.nlm.nih.gov/pubmed/25754933
http://dx.doi.org/10.1002/eji.201445421