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Direct α-synuclein promoter transactivation by the tumor suppressor p53
BACKGROUND: Parkinson’s disease (PD) is a motor disease associated with the degeneration of dopaminergic neurons of the substantia nigra pars compacta. p53 is a major neuronal pro-apoptotic factor that is at the center of gravity of multiple physiological and pathological cascades, some of which imp...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736712/ https://www.ncbi.nlm.nih.gov/pubmed/26833254 http://dx.doi.org/10.1186/s13024-016-0079-2 |